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Revealed
Science has spoken

Having a fat DAD can up your chances of developing female breast cancer

Previously most research focused on how a mum's weight affect their babies' risk of cancer

DADS who are obese are more likely to put their daughters at greater risk of breast cancer, a new study warned.

Daughters of podgy fathers but slim mums, like Family Guy's Peter Griffin, are overweight when born and throughout childhood.

Family Guy's Peter Griffin,
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Peter Griffin is an overweight blue collar worker and main character from animated sitcom Family GuyCredit: Seth MacFarlane

They also have delayed development of their breast tissue as well as increased rates of breast cancer.

The study by Georgetown University Medical Centre, in Washington DC, is the first to examine the effect of a dad being obese on his offspring's future cancer risk.

It suggested carrying extra pounds changes the DNA of a man's sperm which has health consequences to their yet unborn daughter.

Fat man holding a measurement tape against white background. Image shot 2006. Exact date unknown.
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Dads who are overweight could be putting their unborn daughters at risk of breast cancerCredit: Alamy
Breast cancer is the most common type of cancer in the UK
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Breast cancer is the most common type of cancer in the UKCredit: Corbis

Previously most research focused on how a mum's weight affects their babies, but few studies have looked at the influence of a dad being overweight on his baby's future health.

The study published in was carried out in lab mice but scientists said the findings applied to humans.

Assistant professor Dr Sonia de Assis said: "This study provides evidence that, in animals, a fathers' body weight at the time of conception affects both their daughters' body weight both at birth and in childhood as well as their risk of breast cancer later in life.

"Of course our study was done in mice, but it recapitulates recent findings in humans which show that obese men have significant epigenetic alterations in their sperm compared to lean men.

"Our animal study suggests that those epigenetic alterations in sperm may have consequences for next generation cancer risk."

Obesity changes a gene in both the dad's sperm and the daughter's breast tissue
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Obesity changes a gene in both the dad's sperm and the daughter's breast tissueCredit: Getty Images

Researchers found evidence that obesity changes a gene in both the dad's sperm and the daughter's breast tissue, which is linked to alterations in body weight and cancer development.

The assistant professor added: "Until we know about this association in men, we should stick to what we all know is good advice.

"Women - and men - should eat a balanced diet, keep a healthy body weight and lifestyle not only for their own benefit but also to give their offspring's the best chances of being healthy."

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