Four people including police officer injured in horror mass stabbing after car crash in Sydney as suspect arrested

FOUR people including a police officer have been stabbed following a car crash in Sydney.

The 58-year-old alleged attacker used a box cutter to attack a woman in her 40s who was a passenger in the car prior to the crash.

Police said no one was killed in the attack, which came after a "domestic-related" incident in a car that collided with another vehicle in the southern suburb of Engadine.

In a press conference, police superintendent Donald Faulds said the attacker "was armed with what we believe to be a boxcutter.

New South Wales state Police Minister Yasmin Catley said there was no ongoing threat to people of Sydney.

Aerial footage of the scene by the Australian Broadcasting Corp showed two crashed cars cordoned off with police tape.

It is the latest in a series of shocking stabbing attacks in the city this year.

Police say they were called to the scene after witnesses reported a two-vehicle crash in the Engadine area at 9am local time on Sunday.

Officers arrived to find a man, who appeared to have stab wounds, running from the crash.

He was tasered by police who then took him into custody.

A woman - who police say is understood to have been a passenger in the crashed vehicle - was stabbed multiple times.

She has been rushed to hospital.

A male police officer suffered a serious laceration to his left wrist and was taken to hospital,

Paramedics have also treated a victim at the scene at the intersection of Princes Highway and Old Bush Road for cardiac arrest.

Princes Highway has been closed in both directions while emergency crews work.

Sydney has seen a spate of knife attacks this year, prompting the New South Wales state government to toughen its knife laws.

The state parliament passed laws in June giving police electronic metal-detecting scanners to check people without a warrant at shopping centres, sporting venues and public transport stations.

In April, six people were killed and 12 injured in a knife attack at a mall in Sydney's Bondi area.

A New South Wales police spokesman said on the latest incident: "Multiple calls were made to Triple Zero after a two-vehicle crash at the intersection of Princes Highway and Old Bush Road about 9am.

"Officers attached to Sutherland Shire Police Area Command arrived to find a man – who appeared to be suffering stab wounds – allegedly running from the crash scene.

"He was taken into custody with the deployment of a Taser.

"A male police officer suffered a serious laceration to his left wrist believed to have been incurred during the arrest.

"A woman – understood to be a passenger in the crashed vehicle – has been found also suffering multiple wounds.

"A fourth person has been found injured. It’s unclear at this time what that person's involvement is in this incident.

"All four are being treated by NSW Ambulance paramedics.

"More information will be provided when confirmed.

"Anyone with information about this incident is urged to contact Crime Stoppers: 1800 333 000 or //nsw.crimestoppers.com.au. Information is treated in strict confidence."