Savannah Guthrie reveals she suffered a miscarriage and did two rounds of IVF before conceiving her five-year-old son

TODAY Show host Savannah Guthrie has opened up about the struggles she faced when conceiving her youngest child, Charley.

She revealed that she suffered a miscarriage before going through two rounds of IVF to have her son

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Guthrie struggled with infertility, and after having one healthy child, she thought she would never have a second, she said in a recent interview.

Guthrie gave birth to her daughter Vale in 2015 despite many health struggles.

"I knew it was the winning lottery ticket to have one child. So I never dreamed that I would have two," she told in 2019.

"Vale was a miracle, and Charley was a medical miracle."

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At 45 years old, Guthrie knew the best way to conceive a second child would be through In vitro fertilization, or IVF.

IVF can be a tough process both physically and mentally, but Guthrie decided to try.

Before getting pregnant with Charley, Guthrie had to go through not one, but two rounds of IVF.

"I didn’t want to get my hopes up. I just tried to tell myself that it would be OK if it didn’t happen: Maybe it’s not meant for me, and that’s OK because I’ve already been blessed so much in my life," Guthrie told .

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"I’m not entitled to have a baby too. Looking back, that mindset was probably a self-defense mechanism."

Guthrie noted that while some people portray getting pregnant in your 40s as "no big deal," that is typically not the case.

While she is happy that she waited until she was older, and in a more stable career, to conceive, it was the hardest medical decision to make.

"I always say, Charley was, like, the last egg out," she told .

"He really was. And we’re so blessed. Going through what we did, it makes you realize that everything has to go just right to have a healthy baby."

estimates that about 10-15 percent of women in the US will have a pregnancy that ends in miscarriage.

According to , 33 percent of American adults either have tried or know someone who has tried IVF.

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